Eli Lilly Advisor/Senior Advisor Process Chemistry Peptides Oligonucleotides Job: Guide to Requirements, Salary & Application

Introduction

In the competitive world of biopharmaceutical manufacturing, the role of an Advisor/Senior Advisor in Process Chemistry for Peptides & Oligonucleotides at Eli Lilly stands out as a pivotal position. Located in Indianapolis, IN, this opportunity offers a salary range of $121,500 to $198,000 USD annually, reflecting the high expertise required in scaling up production for peptide and oligonucleotide therapeutics. Eli Lilly, a global leader in innovative medicines, is actively seeking seasoned professionals to advance process development in these critical areas.

This guide breaks down the Process Chemistry Advisor job at Eli Lilly, providing pedagogical insights into peptides (short amino acid chains used in drugs like insulin analogs) and oligonucleotides (synthetic nucleic acids for gene therapies). Whether you’re a chemist eyeing Senior Advisor Peptides Oligonucleotides careers or exploring Indianapolis pharma jobs, understanding this role’s demands can position you for success. Posted on September 4, 2025, this listing highlights Eli Lilly’s commitment to diversity through networks like the Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, and Japanese networks.

Analysis

The Eli Lilly Process Chemistry team focuses on optimizing large-scale synthesis and purification of complex biologics. Peptides and oligonucleotides are cornerstone molecules in modern drug development—peptides for targeted therapies and oligonucleotides for RNA-based treatments like those targeting genetic diseases.

Core Responsibilities

Advisors and Senior Advisors lead process optimization, ensuring scalability, cost-efficiency, and regulatory compliance. Key tasks include designing synthetic routes, troubleshooting scale-up issues, and implementing Quality by Design (QbD) principles. In peptides, this involves solid-phase synthesis (SPPS) enhancements; for oligonucleotides, phosphoramidite chemistry and purification via chromatography.

Required Expertise

Candidates typically hold a PhD in Organic Chemistry, Chemical Engineering, or related fields with 8+ years in biopharma process development. Proficiency in analytical techniques like HPLC, MS, and NMR is essential. Experience with GMP manufacturing for peptides and oligonucleotides sets top applicants apart.

Company Context at Eli Lilly

Eli Lilly’s Indianapolis campus is a hub for biotech innovation, housing advanced facilities for oligonucleotide production. The role supports pipeline drugs, aligning with industry trends where the global peptide therapeutics market exceeds $50 billion annually, per verifiable market reports.

Summary

The Eli Lilly Advisor/Senior Advisor – Process Chemistry Peptides & Oligonucleotides position in Indianapolis demands advanced technical skills in biopharma process development. With a competitive salary of $121,500–$198,000 USD/year, it offers stability in a growing field. Diversity networks underscore Lilly’s inclusive culture, making it ideal for global talent in peptide synthesis jobs and oligonucleotide process chemistry careers.

Key Points

Practical Advice

To land this Eli Lilly Senior Advisor Process Chemistry role, tailor your application strategically.

Resume Optimization

Highlight quantifiable achievements, e.g., “Scaled peptide production from 1g to 100kg batches, reducing costs by 30%.” Use keywords like “process chemistry peptides,” “oligonucleotides scale-up,” and “GMP oligonucleotides” to pass ATS filters.

Interview Preparation

Prepare for technical deep dives: Explain DoE for optimizing Fmoc-SPPS yields or ion-exchange purification for impure oligos. Demonstrate soft skills via Lilly’s behavioral interviews, referencing STAR method (Situation, Task, Action, Result).

Application Steps

1. Visit Eli Lilly’s careers portal and search for “Process Chemistry Advisor Peptides Oligonucleotides.”
2. Customize cover letter mentioning alignment with diversity networks.
3. Network on LinkedIn with Lilly process chemists in Indianapolis.
4. Follow up post-application within 1-2 weeks.

Leverage certifications like Six Sigma Green Belt for process improvement edge.

Points of Caution

While promising, approach this peptides oligonucleotides job mindfully:

• High Competition: Pharma roles attract global PhDs; differentiate with patented processes.
• Relocation: Indianapolis offers affordability (cost of living 10-15% below U.S. average), but verify visa needs for internationals.
• Salary Expectations: Range reflects seniority; entry-level won’t qualify—aim for mid-career.
• Work Intensity: Process chemistry involves tight deadlines for clinical trials; expect lab and office hybrid.
• Date Sensitivity: Posted September 2025; apply promptly as listings close quickly.

Comparison

Compared to similar roles, Eli Lilly’s offering excels in compensation and stability.

Vs. Pfizer/Moderna

Eli Lilly provides balanced pay with Midwest perks; Moderna offers higher top-end but higher costs. Peptide expertise transfers well across, per industry benchmarks from Glassdoor and Levels.fyi.

Entry vs. Senior Levels

Advisors (mid-level) focus on execution; Seniors lead innovation—progression requires 3-5 years proven impact.

Legal Implications

This role falls under U.S. employment laws, including the Fair Labor Standards Act (FLSA) classifying it as exempt salaried. Salary transparency complies with Indiana and federal guidelines post-2023 NASDAQ rules for pharma. Eli Lilly adheres to EEOC diversity mandates, evident in networks. Internationals note H-1B visa caps; green card paths via Lilly sponsorship are common but verifiable via USCIS data. No non-compete issues beyond standard NDAs for trade secrets in process chemistry IP.

Conclusion

The Eli Lilly Advisor/Senior Advisor Process Chemistry Peptides & Oligonucleotides position represents a gateway to leadership in biopharma’s future. With robust salary, strategic location, and innovative focus, it’s primed for chemists advancing peptide process development and oligonucleotide manufacturing. Apply now to contribute to life-changing therapies while building a rewarding career in Indianapolis.

This pedagogical overview equips you with actionable knowledge— from synthesis fundamentals to application tactics—ensuring you’re competition-ready.

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